COST Action BM1403 Mini Symposium

On Wednesday morning, prior to the SSP conference, the COST Action BM1403 (Native Mass Spectrometry and Related Methods for Structural Biology) is organising a mini-symposium on topics relevant to the whole Structural Proteomics community, which is open to anyone to attend (SSP conference delegates welcome).

There will be a number of short talks from students and postdocs from within the COST group but importantly, the Working Group leaders will also report on inter-lab comparisons and recommended work practices for several key structural proteomics techniques.

 Venue

 

TU Main Building

Straße des 17. Juni 135

Lecture Hall H0110

Programme

8:50 Welcome

9:00 Valerie Gabelica, Bordeaux: Community standards and recommendations for ion mobility MS (WG1)

9:20 Kasper Rand, Copenhagen: Community standards and recommendations for HDX-MS (WG2)

9:40 Claudio Iacobucci, Halle/Saale: Evaluation of inter-lab comparison and recommendations for xlink-MS (WG2)

10:00 Justin Benesch & Kostas Thalassinos: Computational methods for native & ion mobility MS (WG4)

10:30 Coffee break

11:00 Esben Trabjerg, Zurich: Feasibility of succinimidyl-based crosslinking at slightly acidic conditions

11:20 Shane Chandler, Oxford: Coupling gas-phase HDX to IMS reveals structural transitions as proteins leave their native state

11:40 Jasmin Dülfer, Hamburg: HDX-MS of norovirus capsid proteins

12:00 tbc

8th Symposium on Structural Proteomics

Come join us in Berlin for the 8th SSP from 10-12 October 2018.

PRELIMINARY PROGRAMME

A preliminary programme can be found on the Programme page.

This year’s symposium will focus on the following tracks:
  • Cross-linking/mass spectrometry
  • Surface labelling
  • Ion mobility/native MS
  • Data-assisted modelling
  • Standards
  • New chemistry, instruments, approaches
  • Software in structural proteomics

 

Looking forward to seeing you in Berlin!

https://www.ssp2018.de/

Autumn Workshop in Structural Proteomics Spa Hotel Bomba, Nurmes – Finland, 19-21.9.2018

COST BM1403 Autumn Workshop 2018

  • Organized by EU COST action BM1403 ”Native Mass Spectrometry and Related Methods for Structural Biology” (www.cost.eu/COST_Actions/bmbs/BM1403)
  • A workshop dedicated to the theory and practise of modern techniques in structural proteomics, includingØ Native mass spectrometry (native MS)
    Ø Ion mobility mass spectrometry (IM-MS)
    Ø Hydrogen/deuterium exchange mass spectrometry (HDX-MS)
  • Instructors include world renowned experts in the field: Frank Sobott (Univ. Antwerp/Leeds), Justin Benesch (Univ. Oxford), Kasper Rand (Univ. Copenhagen), Valerie Gabelica (IECB) & Janne Jänis (UEF Chemistry)
  • COST covers travel, accomodation, all meals, free use of spa and social program!
  • Further information & registration: http://structuralproteomics.eu/ -> meetings
  • Spa Hotel Bomba: https://bomba.fi/en/spa

Registration to the event: please send email to janne.janis@uef.fi with short CV and motivation letter (max. 1/2 page) included. The deadline for registrations is 5.9.2018 noon!

COST covers all local costs and makes a contribution to travel costs

* Bus between Joensuu airport/train station and Nurmes on Tuesday 18.9. (17:30-) and  Friday 21.8. (07:30-)

** COST provides support of 400 € for domestic and 580 € for international trainees for accommodation and travel expenses, which can be claimed from COST after the workshop. Accommodation is in single (97 € /night) or double (127 € /night) rooms. 

Trainees pay accommodation directly to the hotel.

COST Progress in Native Mass Spectrometry – Instrumentation and Applications

February 21st to February 22nd, 2018 at TU Wien (Vienna University of Technology), Vienna, Austria.

 

Absolute deadline for registration: Feb 9th, 2018 (e-mail to guenter.allmaier@tuwien.ac.at ).

 

COST Vienna 2018 Flyer

 

February 21st – 22nd, 2018

 

Location

TU Wien (Vienna University of Technology), TUtheSky, 11th floor, Building BA,

Getreidemarkt 9, A-1060 Vienna, Austria

 

Time

Starting time: February 21st, 14:00 (sharp)

Finishing time: February 22nd, 12:30

 

Facts on the Venue

The meeting and the Scientific Presentations will be given on the 11th floor of the Office Building BA.
Coffee breaks and Exhibition (on the first day) will be located on the 2nd floor.

 

 

How to reach us

The conference room is on the 11th floor of office building BA, the coffee breaks and exhibition (on the first day) is on the 2nd floor.

Public transportation:

The address “Getreidemarkt” can be reached by a walk (5-7 min) from the underground station “Karlsplatz” reached via U1, U2 and U4.

A 5 min walk from the station “Museumsquartier” (U2) will lead you also to the highest building in the area.

The inner city can be reached within 10 min walking distance.

By car:

A parking garage is accessible via Lehargasse (€ 3,50 / hour, € 35 daily rate)

Details (maps etc.) on the location can be found on the following website:

https://mass-spec-forum-vienna.conf.tuwien.ac.at/home/

Nearby Hotels

 

Hotel Terminus**
Small Luxury Hotel Das Tyrol****
Time Out City Hotel Vienna
Kolping Wien Zentral **
Hotel Admiral****
nh Wien****
Pension Hotel Mariahilf***
Hotel Savoy Garni***
Hotel Beethoven Wien****
Wombat’s City Hostels Vienna At The Naschmarkt*
Mercure Secession Wien****
Drei Kronen Hotel City***
Best Western Premier Kaiserhof Wien****
Das Triest*****

 

Fast reservation is recommended due to the Viennese ball season.

 

General Information

  • The official language of the Conference is English.
  • Badges will be distributed at the registration desks. Participants without badges will not be admitted to the conference activities. Participants who have not previously registered must register on-site to participate.
  • During breaks coffee or small lunch will be served. Please inform us on your participation during the Welcome evening.
  • A certificate of attendance will be provided on request.
  • All speakers should ensure their presentations are uploaded prior to the session.
  • The meeting organizers cannot accept liability for personal injuries sustained or for loss of or damage to property belonging to Conference participants (or their accompanying persons) either during the conference meetings and post conference activities. Participants are advised to take out adequate personal insurance to cover travel, accommodation, cancellation and personal effects.
  • Free WiFi will be available to all conference guests.

 

Convener

Assoc. Prof. Dr. Martina Marchetti-Deschmann

Univ. Prof. Dr. Günter Allmaier

Vienna University of Technology (TU Wien)

Institute of Chemical Technologies and Analytics

Getreidemarkt 9

A-1060 Vienna

Austria

 

PhD Research Fellowship in Structural Biology and Chromatin at University of Oslo (The Centre for Molecular Medicine Norway – NCMM)

A 3 year PhD fellowship is available in the Group for Chromatin and Structural Biology.

The Group for Structural Biology and Chromatin (Sekulic Group) investigates chromatin biology and epigenetics with a biochemical and structural approach. The project aims at understanding changes in chromatin during mitosis and kinetochore formation. We use various biochemical and biophysical approaches (X-ray crystallography, SAXS, SANS, hydrogen-deuterium exchange …). In addition, we collaborate with cell biology groups to link structure with function.

Sekulic group is affiliated with both the Faculty of Medicine and the Department of Chemistry at the Faculty of Mathematics and Natural Sciences. The PhD student will also benefit from career development programs offered both at UiO as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.

PhD candidate: A three-year position is available immediately. We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterization of proteins and protein complexes. Experience in the field of structural biology and mass spectrometry techniques is an advantage. We offer stimulating environment with excellent working and social benefits.

The purpose of the fellowship is research training leading to the successful completion of a PhD degree.

The fellowship requires admission to the PhD program at the Faculty of Mathematics and Natural Sciences. The application to the PhD program must be submitted to the department no later than two months after taking up the position. For more information see:

http://www.mn.uio.no/english/research/phd/

http://www.mn.uio.no/english/research/phd/application/application.html

The ideal candidate will have:

• A Master’s degree in biochemistry, chemistry, molecular biology or a related area

• Hands-on experience with purification of proteins and assembly of protein complexes

• Ability to independently perform experiments, analyze and interpret the results

• Excellent interpersonal/communication skills

• Excellent written and oral English

• Ability to operate as a team player in a multi-disciplinary environment

The application must include:

• Cover Letter stating motivation and research interests

• CV

• Copies of certificates and grades with explanation of the grading system

• A complete list of scientific publications

• List of references (name, relation to candidate, e-mail and telephone number)

Foreign applicants are advised to attach an explanation of their University’s grading system. Please remember that all documents should be submitted in English.

In accordance with the University of Oslo’s equal opportunities policy, we invite applications from all interested individuals regardless of gender or ethnicity.

UiO has an agreement for all employees, aiming to secure rights to research results a.o.  Note that no one can be appointed for more than one specified period at the same institution.

Salary: The position will be placed as SKO 1017 (position code) with salary depending on qualifications within step 50-57 (NOK 436 900 – 490 900  per year) depending on qualifications and seniority.

Inquiries:

About the position: Group Leader,  Nikolina Sekulic (nikolina.sekulic@biotek.uio.no).

About administrative aspects of the application: Nina Modahl (ninam@ncmm.uio.no).

Please submit your application through the web-based recruitment system  https://www.jobbnorge.no/apps/jobbadmin/Project/Applicants.aspx?jobid=144835

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Training School for Cross-Linking Vienna

Date: 23.10.2017, 9:00 am – 5.00 pm Location: IMBA, Dr. Bohrgasse 3, Lecture Hall

9.00 – 9.15 –Welcome (Frank Sobott, Karl Mechtler,)
9.15 – 10.00 Introduction about Cross-linking (Andrea Sinz, Alexander Leitner)10.00 – 11.00 Cross-linking Strategies I: Non-Cleavable Cross-linkers (Philip Andrews, Alexander Leitner)

11.00 – 11.30 Break

11.30 – 12.30 Cross-linking Strategies II: Cleavable Cross-Linkers (Lan Huang, Andrea Sinz)

12.30 – 14.00 Break
14.00 – 14.30 Cross-linking Harmonization Initiative
14.30 – 15.15 In Vivo Cross-linking experiments (Jim Bruce) 15.15 – 15.30 Break
15.30 – 16.30 Software MeroX (Michael Götze)
16.30 – 17.00 Cross-Linking Modeling (Alexander Leitner, Kostas Thalassinos, Nir Kalisman)

Goals of the Training School:

Protein-protein interactions are one of the main driving forces underlying all cellular processes and the knowledge of protein interfaces is the key to understanding cellular functions. Complementary to the classical methods of structural biology (X-ray crystallography,NMR spectroscopy and electron microscopy), cross-linking combined with mass spectrometry (MS) has developed into an alternative technique to obtain valuable information about the structure and dynamics of macromolecular assemblies in solution.

In this workshop, fundamentals of the cross-linking MS strategy will be introduced. Different cross-linking strategies using non-cleavable and MS- cleavable cross-linkers as well as in vivo cross-linking will be presented. Practical aspects of two complementary software tools (MeroX) and on modeling protein complexes based on cross-linking constraints will be taught. Participants are encouraged to bring their own laptop computers!

Please download the software here: http://www.stavrox.com/Download_MeroX_Win.htm

The training school is funded by the BMBS COST Action Program BM1403 “Native Mass Spectrometry and Related Methods for Structural Biology”

Postdoctoral fellow at University of Oslo

The Group for Structural Biology and Chromatin (Sekulic group) investigates chromatin biology and epigenetics with biochemical and structural approaches. The project aims at understanding changes in chromatin during mitosis and kinetochore formation. We use various biochemical and biophysical approaches (X-ray crystallography, SAXS, SANS, hydrogen-deuterium exchange coupled to MS …). In addition, we collaborate with cell biology groups to link structure with function.

A three-year position is available from August 2017. We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterisation of proteins and protein complexes. Knowledge of chromatin and structural biology and mass spec techniques is an advantage. Recently, our group has obtained a funding for new HDX-MS instrument that is intended to be installed in the fall of 2017 and recruited candidate will help with establishing HDX-MS methods.  We offer stimulating environment with excellent working and social benefits.

Please submit your application through the web-based recruitment system linked here: http://uio.easycruit.com/vacancy/1789507/70932?iso=gb

Application deadline:  31.03.2017.

Best wishes,

Nikolina

HDX-MS Conference, 16-17 May 2017

On behalf of the organizing team, you are invited to the first International Conference on Hydrogen Deuterium Exchange Mass Spectrometry (IC HDX) to be held at AstraZeneca R&D, Gothenburg, Sweden 16-17 May 2017 (with a workshop on 15 May). This conference is aimed at anyone with an interest in using, developing and exploring applications of HDX-MS. The conference includes oral and poster presentations, including several confirmed talks from experts in the field. Suppliers will also be present, offering demos of lab equipment and software.

Abstract submission deadline: 3 March 2017

Details: www.hdxms.org

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Four Industrial PhD Positions in both Siena (Italy) and Copenhagen (Denmark)

VADEMA (Doctoral Industrial School for Vaccine Design through Structural Mass Spectrometry) aims at delivering industry-oriented PhD training in the field of structural mass spectrometry applied to vaccinology. The four selected early-stage researchers (ESRs) will experience an intersectoral training programme encompassing an 18-months internship in Glaxo Smith Kline Vaccines (Siena, Italy), and an 18-months internship at in the Protein Analysis Group of Assoc. Professor Kasper D. Rand (Department of Pharmacy, University of Copenhagen, Denmark). The scope of the projects are to develop a structural mass spectrometry platform, and exploit its application to compare conformation and dynamics of antigens in their native states (membrane) with their recombinant soluble forms (vaccines) and to get a better understanding of the humoral response raised against the two forms.

Read more about the positions and application procedures at http://www.vadema.eu/

Application deadline: 28 February 2017

Minimum monthly salary is DKK 25,579 (taxable) + pension contribution + mobility allowance and family allowance (where applicable).

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Annual Research conference and MC meeting Heraklion, March 19-21

Cost_Crete_Logo

Draft programme

 

Sun 19th             

18:00                   Informal get-together in Heraklion (pre-dinner drinks)

20:00                  Informal dinner in Heraklion, self-organized

 

Mon 20th

9:30                    Coffee, IMBB FORTH

9:50-10:00        Welcome and introductory remarks
COST Chair, F. Sobott, University of Antwerp, Belgium
Local Organizer, M. Aivaliotis, IMBB Forth & University of Crete, Greece

10:00-10:30     Michael Kokkinidis
IMBB Forth & University of Crete, Greece

10:35-10:45    Session 1a introductory remarks
COST Vice-Chair, Sarah Cianferani, University of Strasbourg, France

10:45-11:05    Michal Sharon
Weizmann Institute, Israel

11:10-11:30   Nina Morgner
University of Frankfurt/M., Germany

11:35-11:55   Kostas Thalassinos

UCL London, UK

12:00-13:30   Lunch break & Posters

13:30-13:40  Session 1b introductory remarks
WG1 leader, Michal Sharon, Weizmann Institute, Israel

13:40-14:00  Michael Glocker
University of Rostock, Germany

14:05-14:20  Sneha Chatterjee
University of Antwerp, Belgium

14:25-14:45  Rita Grandori
University of Milano-Bicocca, Italy
14:50-15:05   Johannes Heidemann
Heinrich Pette Institut Hamburg, Germany

15:10-15:40   Coffee break

15:40-16:00   Edwin de Pauw
University of Liège, Belgium

16:05-16:25   Pol Ilag
University of Stockholm, Sweden

16:30-16:35   Daniel Driscoll
University College Cork, Ireland

16:40-17:20   Time for discussion (led by Sarah Cianferani & Michal Sharon)

18:30-19:30        Informal MC discussion (core group + interested MC members)

20:00              Conference (networking) dinner in Heraklion
Organized and paid by COST

Tue 21st

08:00            Formal MC meeting & vote on budget plan, IMBB Forth

10.00           Coffee, IMBB Forth

10:20-10:50   Nelson Barrera, Invited Speaker
Pontificia Universidad Católica, Santiago, Chile

10:55-11:20   Session 2a introductory remarks
Alex Leitner, ETH Zurich, Switzerland

11:20-11:40  Elien Vandermarliere

University of Gent, Belgium

11:45-12:00  Elodie Grifnee
University of Liège, Belgium

12:05-13:00 Lunch break & Posters

13:00-13:15  Session 2b introductory remarks
Kasper Rand, University of Copenhagen, Denmark

13:15-13:35  Jonathan Philips

University of Exeter, UK
13:40-13:55   Esben Trabjerg
University of Copenhagen, Denmark

14:00-14:20    Session 3 introductory remarks
Justin Benesch, University of Oxford, UK
14:20-14:35    SKYPE Perdita Barran
University of Manchester, UK
14:40-14:55    Jean Haler
University of Liège, Belgium

15:00-15:20   Marta Vilaseca
IRB Barcelona, Spain
15:25-16:00        Time for discussion (round table)

From 16:00         Free time!

 

Wed 22nd

Departure


 

For travel info please see the following site:

http://www.tavernarakislab.gr/local_info/141.html

 


 

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