PhD Research Fellowship in Structural Biology and Chromatin at University of Oslo (The Centre for Molecular Medicine Norway – NCMM)

A 3 year PhD fellowship is available in the Group for Chromatin and Structural Biology.

The Group for Structural Biology and Chromatin (Sekulic Group) investigates chromatin biology and epigenetics with a biochemical and structural approach. The project aims at understanding changes in chromatin during mitosis and kinetochore formation. We use various biochemical and biophysical approaches (X-ray crystallography, SAXS, SANS, hydrogen-deuterium exchange …). In addition, we collaborate with cell biology groups to link structure with function.

Sekulic group is affiliated with both the Faculty of Medicine and the Department of Chemistry at the Faculty of Mathematics and Natural Sciences. The PhD student will also benefit from career development programs offered both at UiO as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.

PhD candidate: A three-year position is available immediately. We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterization of proteins and protein complexes. Experience in the field of structural biology and mass spectrometry techniques is an advantage. We offer stimulating environment with excellent working and social benefits.

The purpose of the fellowship is research training leading to the successful completion of a PhD degree.

The fellowship requires admission to the PhD program at the Faculty of Mathematics and Natural Sciences. The application to the PhD program must be submitted to the department no later than two months after taking up the position. For more information see:

http://www.mn.uio.no/english/research/phd/

http://www.mn.uio.no/english/research/phd/application/application.html

The ideal candidate will have:

• A Master’s degree in biochemistry, chemistry, molecular biology or a related area

• Hands-on experience with purification of proteins and assembly of protein complexes

• Ability to independently perform experiments, analyze and interpret the results

• Excellent interpersonal/communication skills

• Excellent written and oral English

• Ability to operate as a team player in a multi-disciplinary environment

The application must include:

• Cover Letter stating motivation and research interests

• CV

• Copies of certificates and grades with explanation of the grading system

• A complete list of scientific publications

• List of references (name, relation to candidate, e-mail and telephone number)

Foreign applicants are advised to attach an explanation of their University’s grading system. Please remember that all documents should be submitted in English.

In accordance with the University of Oslo’s equal opportunities policy, we invite applications from all interested individuals regardless of gender or ethnicity.

UiO has an agreement for all employees, aiming to secure rights to research results a.o.  Note that no one can be appointed for more than one specified period at the same institution.

Salary: The position will be placed as SKO 1017 (position code) with salary depending on qualifications within step 50-57 (NOK 436 900 – 490 900  per year) depending on qualifications and seniority.

Inquiries:

About the position: Group Leader,  Nikolina Sekulic (nikolina.sekulic@biotek.uio.no).

About administrative aspects of the application: Nina Modahl (ninam@ncmm.uio.no).

Please submit your application through the web-based recruitment system  https://www.jobbnorge.no/apps/jobbadmin/Project/Applicants.aspx?jobid=144835

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Postdoctoral fellow at University of Oslo

The Group for Structural Biology and Chromatin (Sekulic group) investigates chromatin biology and epigenetics with biochemical and structural approaches. The project aims at understanding changes in chromatin during mitosis and kinetochore formation. We use various biochemical and biophysical approaches (X-ray crystallography, SAXS, SANS, hydrogen-deuterium exchange coupled to MS …). In addition, we collaborate with cell biology groups to link structure with function.

A three-year position is available from August 2017. We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterisation of proteins and protein complexes. Knowledge of chromatin and structural biology and mass spec techniques is an advantage. Recently, our group has obtained a funding for new HDX-MS instrument that is intended to be installed in the fall of 2017 and recruited candidate will help with establishing HDX-MS methods.  We offer stimulating environment with excellent working and social benefits.

Please submit your application through the web-based recruitment system linked here: http://uio.easycruit.com/vacancy/1789507/70932?iso=gb

Application deadline:  31.03.2017.

Best wishes,

Nikolina

Four Industrial PhD Positions in both Siena (Italy) and Copenhagen (Denmark)

VADEMA (Doctoral Industrial School for Vaccine Design through Structural Mass Spectrometry) aims at delivering industry-oriented PhD training in the field of structural mass spectrometry applied to vaccinology. The four selected early-stage researchers (ESRs) will experience an intersectoral training programme encompassing an 18-months internship in Glaxo Smith Kline Vaccines (Siena, Italy), and an 18-months internship at in the Protein Analysis Group of Assoc. Professor Kasper D. Rand (Department of Pharmacy, University of Copenhagen, Denmark). The scope of the projects are to develop a structural mass spectrometry platform, and exploit its application to compare conformation and dynamics of antigens in their native states (membrane) with their recombinant soluble forms (vaccines) and to get a better understanding of the humoral response raised against the two forms.

Read more about the positions and application procedures at http://www.vadema.eu/

Application deadline: 28 February 2017

Minimum monthly salary is DKK 25,579 (taxable) + pension contribution + mobility allowance and family allowance (where applicable).

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Postdoctoral Position at ETH Zurich / Chemistry

We seek to fill a postdoctoral position in our research group. The topic of the research project will be the coupling of a novel plasma ionization source for high-resolution mass spectrometry with solid-phase microextraction, characterization and further development of this hyphenated method, and development of promising analytical applications. This project is a collaboration with a major manufacturer and supplier of SPME and lab automation devices. State-of-the-art MS instrumentation is available in our group, and world-class departmental facilities (mechanical and electronic workshops, library services, computing facilities, etc.) are accessible at ETH Zurich.

Prerequisites: Ph.D. degree in chemistry or related area, strong background in analytical chemistry and instrumentation, motivated to work with an industrial partner. Further information: see http://www.zenobi.ethz.ch/research/ambient-mass-spectrometry.html. Starting date: January 2017, or upon mutual agreement.

Applications with CV, publication list, and 2 letters of recommendation should be sent directly to Prof. Renato Zenobi, by mid September 2016.

Postdoktoranden-Stelle, ETH Zürich / Chemie

In unserer Forschungsgruppe ist eine Postdoktorandenstelle neu zu besetzen. Das Forschungsthema betrifft die Kopplung einer neuartigen Plasma-Ionisationsquelle für die hochauflösende Massenspektrometrie mit Festphasen-Mikroextraktionsmethode, die Charakterisierung und Weiterentwicklung dieser gekoppelten Analysenmethode sowie die Entwicklung vielverprechender analytischer Anwendungen. Das Projekt ist eine Zusammenarbeit mit einem wichtigen Hersteller und Lieferanten von SPME Materialien und Laborautomations-Geräten.

Voraussetzungen: Abgeschlossenes Doktorat in Chemie oder einem verwandten Gebiet, sehr gute Kenntnisse in Analytischer Chemie, Freude an Instrumenten-Entwicklung und an einer Zusammenarbeit mit einem Industrie-Partner. Weitere Informationen unter http://www.zenobi.ethz.ch/research/ambient-mass-spectrometry.html. Beginn: Januar 2017 oder nach Vereinbarung.

Bewerbungen bis Mitte September 2016 mit CV, Publikationsliste, und 2 Empfehlungsschreiben direkt an Prof. Renato Zenobi

Postdoctoral Position at University of Liverpool

Have proteomics experience and interested in cell signalling/cancer research? A postdoc position is now available with Dr. Patrick Eyers and Prof. Claire Eyers (Centre for Proteome Research) at the University of Liverpool. Application deadline Friday 2nd September.

The laboratories of Dr Patrick Eyers and Professor Claire Eyers evaluate human phosphoproteomes using a variety of approaches, including biochemistry, transcriptomiccs, chemical biology and mass spectrometry. We are looking for an experienced cell signalling or MS-based phosphoproteomics researcher to lead a North West Cancer Research (NWCR) funded project to evaluate the Polo-like kinase 4 signalling pathway and its role in cancer. You will have a PhD in Biochemistry, Pharmacology or a related biological science, a strong interest in protein phosphorylation, and demonstrable knowledge and experience of mass spectrometry for cell signalling analysis. The post is available immediately for 1 year initially, with the possibility of a 2 year extension.

https://www.liverpool.ac.uk/working/jobvacancies/currentvacancies/research/001230/

University of Bordeaux international post-doctoral program

The University of Bordeaux opened a competitive call for its international post-doctoral program (beginning of contract: July to December 2017).

Excellent candidates within 4 years of obtaining their PhD (+ parental leave conditions) are welcome to apply.

Call details: http://idex.u-bordeaux.fr/n/Talents/International-Post-Doctorates/r3137.html

The research project must be supported by a host lab in Bordeaux. My team is willing to support one candidate, with a project in the broad fields of structural mass spectrometry, nucleic acids structure, and/or non-covalent assemblies.

Call deadline: November 27th, 2016.

Interested candidates can email me a CV and a half-page project outline, preferably one month in advance of the call.

I would be grateful if you could forward this announcement to potential applicants.

 

Best regards,

 

Valérie Gabelica.

 

 

Dr. Valerie GABELICA
Research Director (DR2) – Team BiophyMS
ARNA Laboratory (Inserm U1212/CNRS UMR5320/Université de Bordeaux)
valerie.gabelica@inserm.fr
Tel. +33 (0)5 4000 2940
Institut Europeen de Chimie et Biologie

2, rue Robert Escarpit
33607 Pessac, France
www.iecb.u-bordeaux.fr/teams/GABELICA

 

Institute of Clinical Sciences RESEARCH ASSOCIATE

Institute of Clinical Sciences 
RESEARCH ASSOCIATE 
Salary range: £33,860- £42,830 per annum 

 
Applications are invited for a postdoctoral research position in the Reprogramming and Chromatin Group headed by Dr Petra Hajkova at the Clinical Sciences Centre (CSC) in Imperial College London. The group studies molecular mechanisms underlying epigenetic reprogramming in vivo and in vitro (for further information, please visit http://www.csc.mrc.ac.uk/Research/Groups/EDC/ReprogrammingChromatin/)
 
We are looking for an enthusiastic and passionate scientist experienced in the field of mass spectrometry to join our efforts to elucidate molecular mechanisms implicated in the dynamic changes in nucleic acid modifications observed in early mouse embryo, developing germ line and pluripotent stem cells. Our group operates our own QQQ LC/MS instrument (Agilent 6490) and focuses on cutting edge, ultra-sensitive detection of DNA and RNA modifications in minute biological samples (see Amouroux et al, Nat Cell Biol, 2016) .For informal enquiries please contact Dr Petra Hajkova (petra.hajkova@csc.mrc.ac.uk).